The Museum of Curiosity is hosted by the Professor of Ignorance at the University of Buckingham, Professor John Lloyd C.B.E. (of Not the Nine O'Clock News, Spitting Image, Blackadder and QI fame), and the comedian Jimmy Carr.

The Museum invites three guests, a mixture of entertaining experts and expert entertainers, to donate one item each to the museum and explain why it deserves a place in the museum. Ever since someone gave the museum the Big Bang it's been expanding at an alarming rate, and now there's no looking back without the aid of a huge telescope.